Quantitative determination of HBV DNA by comparing the cases before and after treatment.
Number of cases: 25 (n)
Case Selection: Between the ages of 16 and 65, according to the diagnosis standards pf antigen in chronic hepatitis B antibody negative with positive ee, HBV DNA> 1 x 104 cp / mL.
Detection methods: All blood samples were detected by clinical screening Sichuan Center, PCR-ELISA quantitative determination is used in the detection range of 1 x 104-1, 107-8 × HBV-DNA, unit of measure cp / mL.
Plan to address: one suppository provided by Vigconic (International) Ltd. offer. Course of treatment is six months, the follow-up observation after withdrawal lasts six months.
Comment index:
HBV-DNA response after treatment.
HBV DNA response lasted (six months after withdrawal).
Criteria for therapeutic effect:
If HBV DNA volume of 1 × 104 cp / ml: 4.25 (16%)
Keep your answer:
HBV-DNA volume of 1 × 104 cp / ml: 2.25 (8%)
The results of the response time, 16 blood serum samples are detected through fluorimetric quantitative determination by PCR PE.USD instrument, H-7700 in the hospital attached to the Faculty of Medicine, Guangzhou. The result agrees with the Center for Clinical Trials Sichuan. (8 cases among)
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